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SIU Publications
17. Hill, TD, Basnet S, Lepird HH, Rightnowar BW, Moran SD. “Anisotropic Dynamics of an Interfacial Enzyme Active Site Observed Using Tethered Substrate Analogs and Ultrafast 2D IR Spectroscopy” J. Chem. Phys. 2023, 159, 165101
DOI: https://doi.org/10.1063/5.0167991
16. Perera S, Aikawa T, Shaner S, Moran S, Wang L. “Effects of Intramolecular Group and Solvent on Vibrational Coupling Modes and Strengths of Fermi Resonances in Aryl Azides: A DFT Study of 4-Azidotolune and 4-Azido-N-Phenylmaleimide.” J. Phys. Chem. A. 2023, Accepted
DOI: 10.1021/acs.jpca.3c06312
15. Sruthi Sudhakar, Christopher L. Barkau, Ramadevi Chilamkurthy, Halle M. Barber, Adrian A. Pater, Sean D. Moran, Masad J. Damha, P.I. Pradeepkumar, Keith T. Gagnon. "Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly." Journal of Biological Chemistry, 2023, 299, 104700
DOI: 10.1016/j.jbc.2023.104700
14. David A. Price, Poornima Wedamulla, Tayler D. Hill, Taylor M. Loth, Sean D. Moran. "The Polarization Dependence of 2D IR Cross-Peaks Distinguishes Parallel-Stranded and Antiparallel-Stranded DNA G-quadruplexes." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267, 120596
DOI: 10.1016/j.saa.2021.120596
13. Price, D.A.; Hill, T.D.; Hutson, K.A.; Rightnowar, B.W.; Moran, S.D. "Membrane-Dependent Amyloid Aggregation of Human BAX a9 (173-192) ." Protein Science, 2021, 30, 1072-1080
DOI: 10.1002/pro.4053
12. Price, D.A.; Kartje, Z.J.; Hughes, J.A.; Hill, T.D.; Loth, T.M.; Watts, J.K.; Gagnon, K.T.; Moran, S.D. "Infrared Spectroscopy Reveals the Preferred Motif Size and Local Disorder in Parallel Stranded DNA G-Quadruplexes." ChemBioChem, 2020, 21, 2792-2804
DOI: 10.1002/cbic.202000136
Previous Publications
11. Kratochvil H.T.; Carr, J.K.; Matulef, K.; Annen, A.W.; Li, H.; Ostmeyer, J.; Serrano, A.L.; Raghuraman, H.; Moran, S.D.; Skinner, J. L.; Perozo, E.; Roux, B., Valiyaveetil, F.I, Zanni, M.T. “Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.” Science, 2016, 353, 1040-1044
DOI: 10.1126/science.aag1447
10. Zhang, T.O; Grechko, M.; Moran, S.D.; Zanni, M.T. “Isotope labeled amyloids via synthesis, expression, and chemical ligation for use in FTIR, 2D IR and NMR studies.” Methods in Molecular Biology, 2015, 1345, 21-41.
DOI: 10.1007/978-1-4939-2978-8_2
9. Moran, S.D. and Zanni, M.T. “How to Get Insights into Amyloid Structure and Formation from Infrared Spectroscopy” J. Phys. Chem. Lett. 2014, 5, 1984-1993.
DOI: 10.1021/jz500794d
8. Buchanan, L.E.; Carr, J.K.; Fluitt, A.M.; Hoganson, A.J.; Moran, S.D.; DePablo, J.J.; Skinner, J.L.; Zanni, M.T. “Structural motif of polyglutamine amyloid fibrils discerned with mixed-isotope infrared spectroscopy” Proc. Natl. Acad. Sci. U.S.A, 2014, 111, 5796-5801.
DOI: 10.1073/pnas.1401587111
7. Moran, S.D.; Zhang, T.O.; Zanni, M.T. “An alternative structural isoform in amyloid-like aggregates formed from thermally denatured human γD-crystallin” Protein Science 2014, 23, 321-331.
DOI: 10.1002/pro.2422
6. Lam, A.; Moran, S.D.; Preketes, N.; Zhang, T.O.; Zanni, M.T.; Mukamel, S. “Study of the γD-Crystallin Protein Using Two-dimensional Infrared (2D IR) Spectroscopy: Experiment and Simulation”, J. Phys. Chem. B. 2013, 117, 15436-15443.
DOI: 10.1021/jp405159v
5. Moran, S.D.; Zhang, T.; Decatur, S.M.; Zanni, M.T. “Amyloid Fiber Formation in Human γD-crystallin Induced by UV-B Photodamage”, Biochemistry 2013, 52, 6169-6181.
DOI: 10.1021/bi4008353
4. Woys, A.M.; Mukherjee, S. Skoff, D.R.; Moran, S.D.; Zanni, M.T. “A Strongly Absorbing Class of Non-Natural Labels for Probing Protein Electrostatics and Solvation with FTIR and 2D IR Spectroscopies”, J. Phys. Chem. B. 2013, 117, 5009-5018.
DOI: 10.1021/jp402946c
3. Moran, S.D.; Decatur, S.M.; Zanni, M.T. “Structural and Sequence Analysis of the Human γD-Crystallin Amyloid Fibril Core Using 2D IR spectroscopy, Segmental C Labeling, and Mass Spectrometry”, J. Am. Chem. Soc., 2012, 134, 18410-18416.
DOI: 10.1021/ja307898g
2. Moran, S.D.; Woys, A.M.; Buchanan, L.E.; Bixby, E.; Decatur, S.M.; Zanni, M.T. “Two-Dimensional IR Spectroscopy and Segmental C Labeling Reveals the Domain Structure of Human γD-Crystallin Amyloid Fibrils”, Proc. Natl. Acad. Sci. U.S.A, 2012, 109(9), 3329-3334.
DOI: 10.1073/pnas.1117704109
1. Westerlund, K.; Moran, S.D.; Privett, H.K.; Hay, S.; Jarvet, J.; Gibney, B.R.; Tommos, C. “Making a Single-Chain Four-Helix Bundle For Redox Chemistry Studies”, Protein Engineering , Design, and Selection, 2008, 21, 645-652.
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